An inquiry into the effect of instruction in critical thinking upon students in grades ten, eleven and twelve.

Thesis (Ed.D.)--Boston University

A comparison of the composition interests of six hundred sixty students in grades eight through twelve

Thesis (Ed.M.)--Boston Universit

What the guide does not tell you: reflections on and lessons learned from applying the COM-B behavior model for designing real life interventions

Substantial inconsistency exists in the effectiveness of existing interventions to improve heart failure (HF) self-care, which can be partially explained by the fact that self-management interventions often lack theoretical models that underpin intervention development. The COM-B behavior model is a comprehensive theoretical framework that can be used to develop effective, theory-based interventions. The aim of this article is to highlight the challenges and practical solutions when applying the COM-B model to HF self-care, in order to provide useful support for researchers intending to use the model for designing behavior change interventions. “The Behaviour Change Wheel” handbook provides a step-by-step guide to understand and change behavior. When following the guide, some practical and methodological challenges were encountered. Lessons learnt to overcome these challenges are reported. Although the handbook is a comprehensive guide for designing behavior change interventions, a number of challenges arose. For example, the descriptions provided in the guide were not always sufficient to make solid judgments on how to categorize determinants; narrowing down intervention possibilities to a manageable number and prioritizing potential behavior change techniques over others involved a certain amount of subjectivity in an otherwise highly systematic and structured approach. For the encountered challenges, solutions are provided to illustrate how the model was applied practically to design theory-based behavior change interventions. This article provides a useful reference for researchers’ use of the COM-B behavior model, as it outlines challenges that may occur and potential solutions to overcome them

Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice

BACKGROUND: The pathology of Alzheimer's disease (AD) is comprised of extracellular amyloid plaques, intracellular tau tangles, dystrophic neurites and neurodegeneration. The mechanisms by which these various pathological features arise are under intense investigation. Here, expanding upon pilot gene expression studies, we have further analyzed the relationship between Na+/K+ ATPase and amyloid using APP+PS1 transgenic mice, a model that develops amyloid plaques and memory deficits in the absence of tangle formation and neuronal or synaptic loss. RESULTS: We report that in addition to decreased mRNA expression, there was decreased overall Na+/K+ ATPase enzyme activity in the amyloid-containing hippocampi of the APP+PS1 mice (although not in the amyloid-free cerebellum). In addition, dual immunolabeling revealed an absence of Na+/K+ ATPase staining in a zone surrounding congophilic plaques that was occupied by dystrophic neurites. We also demonstrate that cerebral Na+/K+ ATPase activity can be directly inhibited by high concentrations of soluble Aβ. CONCLUSIONS: The data suggest that the reductions in Na+/K+ ATPase activity in Alzheimer tissue may not be purely secondary to neuronal loss, but may results from direct effects of amyloid on this enzyme. This disruption of ion homeostasis and osmotic balance may interfere with normal electrotonic properties of dendrites, blocking intraneuronal signal processing, and contribute to neuritic dystrophia. These results suggest that therapies aimed at enhancing Na+/K+ ATPase activity in AD may improve symptoms and/or delay disease progression

The Ursinus Weekly, March 18, 1940

Board elects Nicholas T. Barry new Ursinus Weekly editor • Weiland to edit 1941 Ruby ; Dubuque is business manager • Law and morals Goodrich\u27s subject • Candidates listed for April elections • C.A. Kulp talks on old-age security • Jr. ticket committee explains special price • Snyder sets April 2 for spring Lantern issue • Members of faculty quizzed in poll express sentiments on third term • 21-year voting age favored by students • Party is planned for conference week-end • I.R.C. quizzed on current events; will admit members • Committee heads are selected for women\u27s May Day pageant • Hal Moyer chosen honorary basketball captain for season • Ursinus players on all-star quintets • Infield and outfield candidates report • Dorm battlers vie Wednesday in gym • Frosh won five of twelve games • John DeBold wins conference trophy • Undefeated Temple beaten by co-eds • Conference committee secures two speakers • Vespers speaker points way to achieve true personality • Temple professor to address pre-medical society Tuesdayhttps://digitalcommons.ursinus.edu/weekly/1838/thumbnail.jp

The Ursinus Weekly, December 8, 1941

Guest vocalists and musical organizations will blend talents in Messiah presentation • Wenhold tells vespers that giving is one of most important virtues • First forum hears discussion of the post-war world • Gordon airs and novel tavern party to highlight gala senior weekend • President McClure calls for balance in time of crisis • Dr. N. W. Winkelman, Penn neurology prof, to address pre-meds • Michael named member of survey committee for secondary schools • Ursinus ranks high in grad school placements; stands 47th in survey of 215 leading colleges • Rec hall to have host, hostess; Appleget plans novelty events • Bomberger memorial maintains unceasing vigil as it celebrates completion of fiftieth year • Federal government to levy 10% tax on admissions to college activities • John and David Garvey present music recital in Bomberger Hall • Bear quintet faces Lehigh in season\u27s opener this Saturday • Twenty-one wrestlers prepare for opener against Kutztown Wednesday • Co-eds have last year\u27s team intact for season\u27s play • Jing Johnson announces athletic award winners • Captains elected! • 20 frosh candidates drill for season\u27s play under coach Pancoast • G-burg\u27s Bullets dominate bears opponent team; Petro unanimous • Bears make all teams of opponents and scribes • Giving: the spirit of Christmas • Vickland and Jamison to handle soprano, tenor parts in Messiahhttps://digitalcommons.ursinus.edu/weekly/1772/thumbnail.jp

Adapting SAM for CDF

The CDF and D0 experiments probe the high-energy frontier and as they do so have accumulated hundreds of Terabytes of data on the way to petabytes of data over the next two years. The experiments have made a commitment to use the developing Grid based on the SAM system to handle these data. The D0 SAM has been extended for use in CDF as common patterns of design emerged to meet the similar requirements of these experiments. The process by which the merger was achieved is explained with particular emphasis on lessons learned concerning the database design patterns plus realization of the use cases.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 4 pages, pdf format, TUAT00

Evaluating the Effectiveness of Undergraduate Clinical Education Programs

Medical schools should use a variety of measures to evaluate the effectiveness of their clinical curricula. Both outcome measures and process measures should be included, and these can be organized according to the four-level training evaluation model developed by Donald Kirkpatrick. Managing evaluation data requires the institution to employ deliberate strategies to monitor signals in real-time and aggregate data so that informed decisions can be made. Future steps in program evaluation includes increased emphasis on patient outcomes and multi-source feedback, as well as better integration of existing data sources